Dental | Reconstruction


Leader Biomedical’s Dental Reconstruction Portfolio offers targeted therapeutic solutions for reconstruction addressing maxillofacial bone defects with eTiss® allografts and demineralised bone matrix (DBM)

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Our allografts are processed with our proprietary eCOO® Technology, a mild and efficient platform using supercritical carbon dioxide (scCO2) to clean, sterilise, and impregnate human and animal-derived bone and tissue with limited use of chemicals.


eCOO® Technology

The eCOO® Technology platform encompasses several technology handles for cleaning, sterilising, and impregnating biological and synthetic grafts. These handles are processing protocols and production methodologies that can be combined, optimised, and applied to various tissues. scCO2 minimally affects the structural integrity of bone and tissue grafts when compared to conventional processing techniques and removes medullary tissues responsible for adverse immune response.

Allografts | Perfecting bone regeneration

eTiss® void fillers

Cancellous and cortical bone chips with sound structural and mechanical properties for filling of bone loss and/or correcting of defects.

  • eCOO® Technology processing ensures excellent osteoconductive properties
  • Forms stable complex with patient’s adjacent bone

eTiss® DBM

Cortical bone demineralised with the goal of exposing encapsulated growth factors, such as bone morphogenetic proteins (BMPs).

  • The presence of BMPs has proven to result in faster bone regeneration
  • Available as putty in a pre-filled syringe for easy application

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